A perimenopause and menopause OS

Welcome to the age of knowing yourself.

A hormonal intelligence platform built for the years no one prepared you for.

Founding cohort · limited seats · founding-member rate locked for life

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01 · The problem

The average woman spends a third of her life in perimenopause and beyond, and almost none of it prepared for.

Doctors get 60 minutes of menopause training in medical school. Search engines send you to forums. Your mother, if you are lucky, offers a shrug. We built Knowher because the version of care that exists is not care. It is guesswork.

85%of women experience symptoms
1 in 3will develop cardiovascular disease post-menopause
60 minaverage menopause training in med school
02 · The daily loop

One small question a day. A record that compounds.

Perimenopause does not announce itself in a single appointment. It shows up as a hundred small moments spread across years. Knowher asks one private question each day, remembers every answer, and turns the pattern into something you can act on, long before it becomes a crisis.

Day 01

Ask

Thirty seconds. One question. No forms, no diagnosis, just what felt different today.

Day 30

Remember

Sage holds every log and every question. The pattern starts to show before you would have noticed it yourself.

Day 90

Anticipate

What is cyclical, what is trending, and what is likely coming next week, with the levers that move it.

Your next visit

Advocate

Your record becomes a brief. You walk in with the questions, not the hope that you will remember them.

This is the part nobody else does. Clinics see you twice a year. Wearables see your body but not your experience. Knowher lives in the years in between, which is where perimenopause actually happens and where prevention is still possible.

See the first ninety days →
03 · What it is

Six things, working together, that finally add up to knowing yourself.

One memory runs through all of them. The daily question feeds it, Sage reads it, the Advocate carries it into the exam room, and your community and clinicians pick up where software should stop.

01

The Daily Question

One private question a day: is this normal? Thirty seconds, and your record gets smarter. No feed, no streaks, no guilt.

The input
02

Sage, your AI right-hand

Sage remembers every log and every question, so she can tell you what is cyclical, what is trending, and what is likely coming. Non-diagnostic, and there when you ask.

The memory
New 03

The Advocate

Walk into every appointment prepared. A brief of questions built from your record, plain-English translations of your notes and labs, and a memory for every "let's watch it."

The action
04

Matched peer pods

Small, matched circles of women at the same stage. Moderated by trained facilitators, anonymous by default, never a public feed.

The room
05

Expert escalation

When a question crosses from information into guidance, you are handed to a menopause-trained clinician or coach. Not a chatbot. Not a "wellness advisor."

The humans
06

Wearable import

Apple Health, Oura, Garmin, Whoop. Your HRV, temperature, sleep, and activity feed one hormonal picture and strengthen every pre-visit brief.

The signal
04 · The Advocate

The AI that stands next to you in the doctor's office.

Visits are getting shorter. Women leave with labs they do not understand, symptoms that were brushed aside, and no record of what was actually said. The system was not built to advocate for you, so Knowher does.

  1. Before

    A brief, not a blank stare

    Questions for your doctor, generated from your longitudinal record, your logged symptoms, and what you want from the appointment.

  2. After

    Your notes, in plain English

    Upload or dictate what happened. The Advocate translates the notes and labs, organizes what was decided, and flags what deserves a follow-up question.

  3. Between

    Open loops, remembered

    If a doctor said "let's watch it," the Advocate remembers, and resurfaces it at the right time.

What it never does. It never diagnoses, never contradicts your clinician, and never tells you your doctor missed something. Every output is education and visit preparation. When a question needs a human, it hands you to one.
05 · Why community

Menopause is a medical condition and a social one.

Perimenopausal women report the highest rates of loneliness of any life stage after widowhood. That isolation is not incidental. It drives depression, sleep collapse, and cardiovascular risk. We built the platform around community for the same reason we built it around clinicians: because the evidence says both are required.

  • Small, matched peer circles
  • Moderated by trained facilitators
  • Anonymous by default
  • Never a public feed. Never an algorithm.
Two women's hands clasped together
"For the first time I'm in a room where I don't have to explain what I mean."Knowher pilot member, 47
06 · How it works

Three weeks in, Knowher knows your pattern. Three months in, it can predict it.

  1. Week 01

    Baseline

    A 12-minute intake with a clinician. Connect a wearable. Set the symptoms you care about most.

  2. Week 02

    Pattern

    Daily one-tap check-ins. Knowher starts to correlate hot flashes with sleep debt, mood with cortisol, joint pain with cycle phase.

  3. Week 03

    Signal

    Your first hormonal report. What is cyclical, what is trending, and what to bring to your next clinician visit.

  4. Month 03

    Prediction

    Knowher tells you what your next two weeks are likely to look like, and which levers move it.

07 · Roadmap

Phase 2: cardiovascular intelligence.

Cardiovascular disease is the leading cause of death in women, and menopause is the single most predictive life stage for it. Almost no product treats the two as connected. We do. Phase 2 brings continuous cardiovascular monitoring into Knowher: cholesterol, blood pressure, HRV, and hormone data in one place, with clinician-reviewed alerts when something is changing.

Now
Hormonal intelligence

The daily question, Sage, the Advocate, peer pods, expert escalation, wearables.

Phase 3
Longevity and bone

Bone density, muscle mass, cognitive baselines. The second half of life, measured.

Des Trueblood and Natalia Salter, co-founders of Knowher
08 · Why we are building this
"We started Knowher because the version of care we needed didn't exist, and the women we love kept telling us theirs didn't either. We're building the platform we wish had been waiting for us."

Des Trueblood and Natalia Salter, co-founders

Clinical council

Board-certified OB/GYNs and menopause-trained specialists shape every feature we ship.

Data ethics

Your data is never sold. Ever. Export or delete anything, any time.

Built by women who have lived it

Every product decision passes the "would we send this to our sister?" test.

Backed by evidence

Every claim on this site is sourced. Ask us for the reading list.

09 · Questions

What people ask us first.

When does the app launch?

The founding cohort begins onboarding this quarter. Waitlist members get first access, a founding-member rate locked for life, and our perimenopause field guide delivered to their inbox this month.

Who is Knowher for?

Women in perimenopause, menopause, or the years leading in. If you are between 35 and 60 and your body is doing things it did not use to, you are who we built this for.

Is this a replacement for my doctor?

No. Knowher makes the appointment you already have better. You show up with data, patterns, and questions instead of vague symptoms, and the Advocate never diagnoses or contradicts your clinician.

Does Knowher diagnose anything?

No. Sage and the Advocate explain your own records in plain English and help you ask better questions. Anything that crosses from information into guidance goes to a menopause-trained clinician or coach.

How do you handle my data?

Encrypted, never sold, exportable, deletable. We treat health data the way we would want ours treated, because ours is in here too.

How much does it cost?

Founding cohort pricing is disclosed at invitation. It is meaningfully lower than what the platform will list for at general launch, and that rate stays locked as long as you stay a member.

Be among the first to know yourself.

Join the founding cohort. We are opening the platform to a small group of women first, and we would like you to be one of them.

Founding member rate locked for life · perimenopause field guide sent this month

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